摘要
精原干细胞(SSC)在睾丸曲细精管内微环境的精确调控下,只能单向分化为精子。然而,SSC可在特定条件下转化为多能干细胞,甚至直接重编程转分化为功能性终末分化细胞。该特殊潜能使其在再生和精准医学领域具有很好的运用前景。
Under the testicular seminiferous tubule microenvironment control,spermatogonial stem cells（ SSC） can only differentiate into sperms. Recent studies have shown that SSC may reprogram into pluripotent stem cells,or even directly reprogramming transdifferentiation into functional terminally differentiated cells under certain conditions in vitro. This potential of SSC makes it potential in the regenerative medicine and precise medicine application.
出处
《基础医学与临床》
CSCD
2016年第12期1728-1732,共5页
Basic and Clinical Medicine
基金
国家自然科学基金青年课题(81501330)
三峡大学人才启动基金(KJ2014B066)
关键词
精原干细胞
转化
转分化
spermatogonial stem cell
conversion
transdifferentiation
