前列腺癌诊断中经直肠超声引导下穿刺活检的应用分析

The application of transrectal ultrasound-guided biopsy in the diagnosis of prostate cancer [

目的探讨经直肠超声引导下穿刺活检诊断前列腺癌的临床价值。方法随机选取2013年1月至2015年5月本院体检收治的前列腺癌疑似患者329例，所有患者前列腺特异性抗原（ProstateSpecificAntigen，PSA）密度均在0．15ng／cm。以上，且经由直肠指诊完成初步诊断，在直肠超声引导下对所有患者实施前列腺外腺6点穿刺活检，并根据活检结果对患者完成诊断。结果本次研究中，31．31％前列腺癌患者经穿刺活检得到确诊，52．58％患者确诊为良性前列腺增生症（Benignprostatichyperplasia，BPH）；前列腺癌组患者的PSA密度明显高于BPH组，前列腺体积明显小于BPH组，差异有统计学意义（P〈0．05）。结论直肠超声引导下行前列腺穿刺活检是一种有效的前列腺癌诊断方法，有助于提高早期诊断准确率，有利于早期治疗的开展，同时可结合患者的前列腺体积及PSA密度等指标对患者的病情进行综合判断。

Objective To discuss the clinical value oftransrectal ultrasound-guided biopsy in the diagnosis of prostate cancer. Methods 329 examined patients with suspected prostate cancer admitted to our hospital from January 2013 to May 2015 were randomly selected. Prostate specific antigen （PSA） density of all patients were all over 0.15 ng/cm3, initial diagnosis through digital rectal examination. All patients underwent prostate outer gland 6：00 biopsy guided by transrectal ultrasound, completing the diagnosis according to biopsy results. Results In this study, 31.31% of patients with prostate cancer were diagnosed by biopsy, 52.58% of patients diagnosed with benign prostatic hyperplasia （BPH）. PSA density in prostate cancer group was significantly higher than that in BPH group, prostate volume was significantly less than that in BPH group, with statistically significant difference （P〈0.05）. Conclusion Transrectal ultrasound-guided prostate biopsy is an effective method of the diagnosis of prostate cancer, which can improve the accuracy of early diagnosis, is conducive to early treatment. We can comprehensively judge patients＇ condition combined with prostate volume, PSA density, and other indicators.