营养状况与慢性阻塞性肺疾病急性加重的相关性研究

Correlation between nutrition therapy and AECOPD patients chronic obstructive pulmonary disease

目的本文主要探讨加强对慢性阻塞性肺疾病急性加重期(AECOPD)患者及早进行营养支持干预治疗后,患者免疫系功能状态、肺通气功能、血气分析、住院时间和病死率等影响患者病情进展及预后的相关性研究。方法将120例急性加重期的慢性阻塞性肺疾病患者随机分为两组,均按照常规给予治疗,营养支持组加用营养支持治疗方案。观察两组患者的营养状况、免疫功能、肺通气功能、动脉血气分析和住院时间、病死率。结果营养支持组患者的营养状态、免疫系统的功能、肺通气功能、动脉血气分析情况明显改善(P<0.05),住院时间缩短、疾病发作次数减少、病死率下降。结论合理的加强营养支持治疗方案更加有利于AECOPD患者的康复,延缓其病情进展速度及改善患者预后的一种重要的综合治疗手段。

Objective To explore the correlation of nutrition therapy with immune function, pulmonary ventilation function, blood gas analysis, hospital stay and mortality in AECOPD patients chronic obstructive pulmonary disease. Methods 120 AECOPD patients were randomly divided into two groups. The control group was given conventional therapy, and the treatment group was given nutrition support. Their respiratory function, immune function changes, arterial blood gas , the average hospital stays and mortality were observed. Results The improvement of nutrition state, respiratory function, immune function and blood gas analysis was more pronounced in the treatment group than in the control group （ P 〈 0. 05 ）, and the duration of hospital stay, disease attack and mortality were lower in the treatment group than in the control group. Conclusion The reasonable nutrition support is helpful for the rehabilitation of AECOPD patients.