中心静脉导管相关血流感染的预警信息系统干预研究

Effect study of nosocomial infection early warning information system on the central line-associated bloodstream infections

目的通过对外科重症监护病房中心静脉置管相关血流感染(CLBSI)在医院感染预警信息系统(NIEWIS)应用前后的对比,评价预警信息系统在预防和控制CLBSI发生的有效作用。方法对2010-2013年进行中心静脉置管的1 091例患者进行前瞻性调查,将采取预警信息系统前后时段的置管情况、导管相关血流感染率进行对比。结果 1 091例患者中,总置管日为11 797d,16例发生导管相关血流感染,千日感染率为1.36‰;共检出30株病原菌,以革兰阴性菌为主,共14株占46.67%;采取措施前后(前2年与后2年)感染率发生变化,差异有统计学意义(P<0.05)。结论预警信息系统的应用可以有效预防CLBSI。

OBJECTIVE To compare the difference before and after using nosocomial infection early warning information system（NIEWIS）in surgery intence care unite for the central line-associated bloodstream infections（CLBSI）,so as to measure and evaluate the effectiveness of the NIEWIS in prevention and control on CLBSI.METHODS A total of 1091 cases of patients with central venous catheter were investigated prospectively from 2010 to 2013.The cathetering condition and the CLBSI rates were compared before and after using NIEWIS.RESULTS In the total of 11797 cathertering dates,there were 16 patients with CLBSI out of 1091 patients with the central venous catheter.The infection rate in thousand days was 1.36‰.Totally there were 30 strains of pathogens were detected,mainly gram-negative bacteria,14 strains,accounting for 46.67%.The difference between before and after using this system（2years before and 2years later）was significant,the infection rates changed（P〈0.05）.CONCLUSION Adopting NIEWIS could prevent CLBSI effectively.