静脉用药调配中心成品不合格的原因探讨与对策

Reasons and Countermeasures for Unqualified Finished-infusion in Pharmacy Intravenous Admixture Service

目的探讨静脉用药集中配置中心成品不合格的常见原因,制定相应的解决措施和对策。方法根据解放军251医院静脉用药集中配置中心2012年3月1日—2014年12月31日成品不合格的登记情况,计算和比较各个不同时期的不合格成品的发生率,并对各配置环节出现的各类问题分类汇总,分析比较。结果引起成品不合格的原因主要有漏液、胶塞碎屑、不溶性微粒、贴错标签和加药错误,漏液引起的不合格率居首位。通过采取相应对策后,成品不合格率呈逐年下降趋势。结论定期对成品不合格的原因进行统计分析,制定正确的规章制度和标准操作规程,强化业务培训,加强药品科学化管理可有效降低成品不合格的发生率。

Objective To analyze the causes of unqualified finished-infusion in pharmacy intravenous admixture service（ PIVAS） and to formulate countermeasures. Methods According to the unqualified finished-infusion registration of PIVAS at our hospital from Mar 1,2012 to Dec 31,2014,the incidence of unqualified finished-infusion in different periods was calculated and compared,and the problems in the whole process of admixture were classified and summarized. Results Causes of unqualified finished-infusion were summarized as follows： leakage,fragments of rubber stoppers for injection bottles,particulate matter,mislabeled products and adding of wrong drugs.The unqualified products caused by leakage ranked first. After countermeasures were taken,the rate of unqualified products decreased year by year. Conclusion The incidence of unqualified finished-infusion by making regular statistical analysis of reasons for unqualified finished-infusion,for mulating rules,regulations and standard procedures,and enhancing professional training and scientific management.