胃癌潜在预后分子标志物的研究进展

Progress in the potential prognosis-related molecular markers of gastric cancer

胃癌是中国最常见的恶性肿瘤之一,常规手术治疗后患者的预后千差万别。随着分子生物学的发展,胃癌患者的预后判断也有了新的评估方式。我们从免疫相关分子、生物代谢相关分子、肿瘤相关基因、信号转导通路及经典预后分子5个方面对胃癌预后分子标志物进行综述。

Gastric cancer is the most common malignant tumor in China. These patients often face differents prognosis after operation. With the development of molecular biology,we can assess the prognosis of patients with gastric cancer by new methods. This paper reviewed prognosis-related molecular markers of gastric cancer from five aspects,including immune molecules,biological metabolism molecules,tumor-re-lated genes,signal transduction pathways and classic prognostic molecules to assist clinical treatment.