采用不同麻醉方式用于小儿补牙的临床效果和安全性比较

Comparison of the clinical efficacy and safety of different anesthesia methods on pediatric dental filling

目的:比较异丙酚复合低剂量的氯胺酮麻醉及单独氯胺酮麻醉用于小儿补牙的临床效果和安全性。方法:随机将在我院补牙的70例患儿均分为两组,对照组采用单独氯胺酮麻醉,观察组采用异丙酚复合低剂量的氯胺酮麻醉,比较两组的麻醉效果、不良反应以及复查结果。结果:对照组的麻醉起效时间、完全清醒时间、出院时间、麻醉后心率、手术结束时心率以及氯胺酮用量均显著长于或高于观察组(P<0.05);对照组的不良反应发生率显著高于观察组(P<0.05);两组麻醉前心率、充填体脱落率、新发或再发龋率、继发龋率差异均无统计学意义(P>0.05)。结论:异丙酚复合低剂量的氯胺酮麻醉用于小儿补牙时麻醉起效快,术后苏醒快,安全可靠,值得在儿牙科麻醉中广泛使用。

[Abstrat] Objective： To compare the clinical efficacy and safety between propofol combined with low dose ketamine anesthesia and individual ketamine anesthesia on pediatric dental filling. Methods： A total of 70 pediatric patients for dental surgery in our hospital were selected as study subjects. According to a random number table method,the pediatric patients were randomly divided into observation group and control group,each group with 35 cases. The control group was treated with individual ketamine anesthesia,while the observation group with propofol combined with low dose ketamine anesthesia. Clinical anesthesia effects,adverse reactions and reexamination results between the two groups were compared. Results： Onset time of anesthesia,awake time,discharge time,heart rate after anesthesia,heart rate at the end of operation and amount of ketamine in the control group were significantly higher than that in the observation group（ P 〈 0. 05）; Adverse reaction incidence of the control group was significantly higher than that of the observation groups（ P 〈 0. 05）; Heart rate before anesthesia,expulsion rate of filling body,the rate of new or recurrent caries and secondary caries rate of the two groups had no significant differences（ P 〉 0. 05）. Conclusion： The application of propofol combined with low dosing ketamine anesthesia on pediatric dental filling has advantages of rapid onset of anesthesia and fast postoperative recovery.That is to say,the application of propofol combined with low dose ketamine anesthesia should be widely used on pediatric dental filling.