呋塞米联合依那普利在慢性肺源性心脏病心力衰竭治疗中的应用

Application of Furosemide combined with Enalapril in treating heart failure due to chronic pulmonary heart disease

目的 研究呋塞米联合依那普利治疗慢性肺源性心脏病心力衰竭的临床效果。方法 选取2014年5月~2016年5月我院收治的慢性肺源性心脏病心力衰竭患者92例,随机分为对照组和治疗组,每组46例。对照组采用依那普利治疗,治疗组采用呋塞米联合依那普利治疗。比较两组治疗前后相关生化指标水平的改善幅度、药物治疗效果、心力衰竭症状消失时间、心脏病药物治疗总时间、用药期间出现的相关不良反应。结果 治疗组用药治疗前后相关生化指标水平的改善幅度明显大于对照组,心力衰竭症状消失时间、心脏病药物治疗总时间明显短于对照组,药物治疗效果明显优于对照组（P〈0.05）。两组的不良反应发生情况差异无统计学意义（P〉0.05）。结论 呋塞米联合依那普利治疗慢性肺源性心脏病心力衰竭的临床效果非常明显。

Objective To study the clinical effect of Furosemide combined with Enalapril treating heart failure due to chronic pulmonary heart disease.Methods 92 patients with heart failure due to chronic pulmonary heart disease treated by our hospital from May 2014 to May 2016 were selected and they were randomly divided into control group and treatment group,and each group had 46 cases.Control group was treated by Enalapril,while treatment group was treated by Furosemide combined with Enalapril.The improvement degree of related biochemical index level before and after treatment,drug treatment effect,disappear time of heart failure symptom,total time of drug treatment for heart disease and related adverse reaction during treatment between two groups was compared respectively.Results The improvement degree of related biochemical index level before and after treatment in treatment group were obvious larger than those in control group and disappear time of heart failure symptom and total time of drug treatment for heart disease in treat- ment group were obviously shorter than those in control group,and drug treatment effect in treatment group was obvi- ously better than that of control group （P〈0.05）.There was no statistical difference of incidence of adverse reaction be- tween two groups （P〉0.05）.Conclusion Furosemide combined with Enalapril treating heart failure due to chronic pul- monary heart disease has a very obvious clinical effect.