急性脑梗死患者颈部粥样斑块与微栓子的相关性研究

Correlation between carotid atherosclerotic plaque and microemboli in patients with acute cerebral infarction

目的探讨脑梗死患者颈动脉粥样斑块与微栓子的相关性。方法对96例急性脑梗死患者行颈动脉超声检查及经颅多普勒(TCD)超声脑动脉微栓子监测,分析颈动脉斑块部位、性质、数量的特征及与微栓子的相关性。结果脑梗死患者颈动脉粥样硬化斑块的发生率60.42%,显著高于健康体检人群19.15%(P=0.000)。颈总动脉分叉处为斑块的好发部位。96例患者微栓子阳性率为29.17%。结论颈总动脉分叉处斑块、不稳定斑块及多部位斑块与微栓子具有显著相关性。

Objective To explore the correlation between carotid atherosclerotic plaques and microemboli in patients with acute cerebral infarction. Methods A total of 96 patients with acute cerebral infarction were conducted with carotid artery ultrasonography and transcranial Doppler（ TCD） ultrasound to monitor cerebral arterial microemboli. Correlation between the characteristics of carotid artery plaque location,nature,quantity and microemboli was analyzed. Results The incidence rate of carotid atherosclerotic plaque in patients with cerebral infarction was 60. 42%,which was significantly higher than 19. 15% in healthy controls（ P = 0. 000）. The bifurcation of common carotid artery is the predilection site of atherosclerotic plaques. The positive rate of microemboli was29. 17% in 96 patients with acute cerebral infarction. Conclusion The plaques at common carotid artery bifurcation,unstable plaque or multiple sites plaque are correlated with microemboli.