植物类中药材及饮片中18种重金属及有害元素研究

Determination of 18 Heavy Metal and Hazardous Elements in Chinese Medicinal Material by ICP-MS

建立植物类中药材及饮片中铅、镉、总砷、总汞、铜、锑、锡、铬、镍、钡、锰、铊、银、铍、镝、铝、硒、钼共18种重金属及有害元素含量的检测方法和限量。样品经微波消解处理后,采用电感耦合等离子体质谱法（ICP-MS）对100批植物类中药材中的重金属及有害元素进行测定和方法研究。各元素线性关系良好,相关系数（r）均大于0.999 5,方法检出限为0.000 22-0.023 0 mg/kg,回收率为90.2%-108.7%,相对标准偏差为1.8%-4.9%。该方法准确、简便、灵敏,可为植物类中药材中重金属及有害元素的检测与控制提供方法参考。

To determine 18 hazardous elements including Pb, Cd, As, Hg, Cu, Sb, Sn, Cr, Ni, Ba, Mn, T1, Ag, Be, Dy, A1, Se, Mo in 100 samples of Chinese medicinal material. The samples were prepared through microwave digestion and analyzed by inductively coupled plasma mass spectrometry（ICP- MS）. The calibration curves of 18 hazardous elements were linear in the certain concentration ranges, with correlation coefficients （r） more than 0. 999 5. Detection limits of the method were in the range of 0. 000 22 -0. 023 0 mg/kg. The recoveries were in the range of 90. 2% -108.7% withRSDsofl. 8% -4.9% could provide a reference for determination The method is highly sensitive, rapid and accurate, and of hazardous elements in Chinese medicinal material.