“正虚伏毒”为肺癌发病的核心病机

Discussion on the core pathogenesis of lung cancer with “deficiency of vital qi and hidden toxin”

人口老龄化导致肺癌高危人群迅速扩大,而早期诊断技术的发展促使肺癌早期患者比例不断升高。针对高危人群和术后患者进行早期干预,预防肺癌的发生和转移是提高总体生存期的关键。现代医学针对这一群体尚缺乏理想的干预手段,中医治疗肿瘤的指导思想及诊疗理念也多基于晚期患者形成。因此该群体的干预与治疗亟待新理论、新方法的指导。根据中医学对人体生命活动的认识特点,结合现代肿瘤学的最新进展,提出"正虚伏毒"为肺癌发病的核心病机的观点,并进行系统阐述,以期抛砖引玉,为中医药防治肺癌提供有力的理论指导,同时也是一次融合现代医学最新进展实现中医理论创新的有益尝试。

The aging population results in the rapid expansion of high-risk patients with lung cancer,while the early diagnosis technology increases the proportion of patients with lung cancer at early stage. Early intervention on high-risk patients and postoperative patients to prevent the occurrence and metastasis of lung cancer is the key to improve the overall survival. Due to lack of effective means of intervention for this group in modern medicine,the guiding ideology and diagnosis and treatment concept of traditional Chinese medicine in the treatment of cancer are mainly based on patients at advanced stage. New theories and methods are urgently required to guide the intervention and treatment for this group. Based on the classical theory of traditional Chinese medicine on the understanding of human life activities,combined with the latest development of modern oncology,this paper puts forward and systematically elaborates that ＂ deficiency of vital qi and hidden toxin＂is the core pathogenesis of lung cancer,which provides sound theoretical guidance for traditional Chinese medicine in the prevention and treatment of lung cancer. Meanwhile,it serves a meaningful attempt to realize the theoretical innovation of traditional Chinese medicine through combining with the latest development of modern medicine.