4-[2-(1-哌啶乙氧基)]苯甲酸盐酸盐的合成工艺改进

Improved Synthesis of 4-[2-(1-Piperidinyl)ethoxy] benzoic Acid Hydrochloride

以对羟基苯甲酸酯为原料 ,通过与二溴乙烷烃化、哌啶胺基化、水解得到高收率的 4 [2 (1 哌啶乙氧基 )

4-[2-(Piperidinyl)ethoxy] benzoic acid hydrochloride was synthesized in high yield through reaction of methyl 4 hydroxybenzoate with 1,2 dibomoethane and piperridine and finally hydrolysis.