体外受精-胚胎移植患者的心理现状与妊娠结局

Analysis on the relationship between the psychological status and the pregnancy outcome of IVF-ET patients

目的观察不孕患者在接受体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)治疗过程中心理变化的特点,并分析其妊娠结局,为日后临床护理工作提供依据。方法选取IVF-ET患者80例,根据妊娠结局分为妊娠组与未妊娠组,采用心理相关量表对患者在治疗过程中的心理特点进行调查,包括一般情况问卷、艾森克人格问卷、症状自评量表、焦虑自评量表、抑郁自评量表。结果妊娠组与未妊娠组的E(内外向)分值、N(神经质)分值、P(精神质)分值、L(说谎)分值间差异无统计学意义(P>0.05);未妊娠组SCL-90各因子分、总分、总均分均明显高于妊娠组(P<0.05);未妊娠组与妊娠组焦虑程度差异无统计学意义(P>0.05),而未妊娠组抑郁程度显著重于妊娠组(P<0.05)。结论患者的心理状态与妊娠结局有关,这对护理工作具有指导意义,临床治疗应与心理干预相结合,关注患者心理健康对妊娠结局的影响,提高妊娠率。

Objective To investigate the psychological changes of infertile patients undergoing in vitro fertilization-embryo transfer（IVF-ET） and to analyze the pregnancy outcome in order to provide basis for future clinical practice. Methods Eighty patients for IVF-ET treatment were chosen. According to the pregnancy outcome, patients were divided into pregnant group and non-pregnant group, by using psychological scales, the study was to study the psychological characteristics of those patients during the treatment process, including information questionnaire, Eysenck Personality Questionnaire （EPQ）, Symptom Checklist-90 （SCL90）, Self- Ratinganxiety Scale （SAS） and Self-Rating Depression Scale （SDS）. And then analyzed the correlation between the indexes of the two groups. Results There is no significant difference （P〉0.05） in E （extroversion）store, N（neuroticism） score,P（psychoticism） score and L（lie） score between pregnant women and non-pregnant women. Every factor marks, the total marks and mean marks of SCL-90 for non-pregnant women was higher than those of pregnant women （P〈0.05）; there is no difference in SAS score between the two groups, SDS score of nonpregnant women was significantly higher than that of pregnant women（P〈0.05）. Conclusion There is significant correlation between the psychological state of the patient and pregnancyoutcome. This finding has guiding significance for nursing. In order to improve the pregnancy rate, clinical treatment should be combined with psychotherapy. Attention should be paid to the impact of patients＂ mental health on pregnancy outcomes.