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Th17细胞和IL-17在小鼠寄生虫免疫中的作用 被引量:2

Roles of Th17 Cells and IL-17 in the Immunity to Parasite of a Mouse
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摘要 Th17细胞(T helper 17 cells,Th17)是CD4^+T细胞分化的亚群细胞之一,能够特异性地分泌细胞因子IL-17(interleukin-17,IL-17),通过IL-17、IL-21、IL-23等细胞因子介导炎症反应和针对细菌的抗感染免疫,同时在寄生虫免疫中发挥重要作用。 Th17 cells(T helper 17 cells), one of cell subsets which differentiate from CD4~+T cells, can specifically secrete the cytokine IL-17A(IL-17), mediate an inflammatory response and anti-infection immunity against bacteria by IL-17, IL-21 and IL-23, and play a significant role in the immunity to parasite.
出处 《畜牧与饲料科学》 2016年第11期104-108,共5页 Animal Husbandry and Feed Science
基金 中国博士后科学基金面上项目(2014M561308) 吉林省科技厅项目(20160520180JH) 吉林省教育厅项目
关键词 TH17 IL-17 寄生虫免疫 细胞因子 Th17 IL-17 immunity to parasite cytokine
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  • 1沈立松,李美星,葛海良.Foxp3对CD4^+CD25^+调节性T细胞中基因的调控作用[J].现代免疫学,2009,29(1):72-75. 被引量:6
  • 2Ivanov 1I , Mekenzie BS, Zhou L, etal. The orphan nuclear receptor ROR-rt directs the differentiation program of pro-inflammatory ILl7+ T helper eells[J]. Cell, 2006,126 : 1121- 1132.
  • 3Kolls JK, Linden A. Interleukin-17 family members and in flammation[J]. Immunity, 2004,21:467 -476.
  • 4Zheng Y, Danilenko DM, Valdez P, etal. Interleukin-22, a T(H) 17 ctykoine mediates IL-23-induced dermal inflammation and acanthosis[J].Nature, 2006,445:648-651.
  • 5Nurieva R, Yang XO, Martinez G, et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells [J]. Nature, 2007,448:480-483.
  • 6Zhou L, Ivanov ]I , Spolski R, etal. IL-26 programs T(H) - 17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways[J].Nat Immunol, 2007,8: 967 -974.
  • 7Jiang SP. Regulatory T cells and Clinical Application [M]: New York. Springer Science+Business Media, LLC. 2008:111- 114.
  • 8Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmen tal pathways for the generation of pathogenic effector Thl7 and regulatory T cells [J]. Nature, 2006,441 :235-238.
  • 9Voo KS, Wang YH, Santori FR, et al. Identification of IL- 17-producing Foxp3+ regulatory T cells in humans[J]. PNAS, 2009,106 : 4793-4798.
  • 10Sakaguchi S. Naturally arising Foxp3-expressing CD25^+ CD4^+ regulatory T cells in immunological tolerance to self and non self[J]. Nat Immunol, 2005,6:345-352.

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