影响中心性浆液性脉络膜视网膜病变预后的相关因素

Prognostic factors associated with central serous retinopathy

目的:探讨影响中心性浆液性脉络膜视网膜病变(central serous chorioretinopathy,CSC)预后的相关因素。方法:选取我院2013-01/2015-01收治的CSC患者75例150眼作为研究对象,进行回顾性分析导致CSC患者预后不良的相关因素。结果:患者预后良好46例92眼(61%),预后不良29例58眼(39%)。预后良好与预后不良患者在性别、年龄方面比较差异均无统计学意义(P>0.05),在病程、渗漏类型、渗漏点距离、渗漏面积方面比较,差异具有统计学意义(P<0.05)。多因素分析显示病程、渗漏类型、渗漏点距离、渗漏面积均是CSC预后不良的危险因素(P<0.05)。病程、渗漏类型、渗漏位置、渗漏面积均与CSC预后不良呈正相关关系(r=0.367、0.269、0.518、0.325,P均<0.05)。结论:导致CSC预后不良的因素较多,病程、渗漏类型、渗漏点距离、渗漏面积均是CSC预后不良的危险因素。

AIM： To investigate the related factors affecting the prognosis of central serous retinopathy（CSC）. METHODS： A total of 75 patients with CSC were selected in our hospital from Jan.2013 to Jan.2015 as the object of study. The clinical data of patients were retrospectively analyzed, and fundus fluorescence angiography for patients. The cause of the related factors of poor prognosis in patients were analyzed. RESULTS： A total of 46 cases of patients 92 eyes, 61% with good prognosis, 29 cases（58 eyes）of poor prognosis, accounting for 39%. Comparison of good prognosis and poor prognosis of patients in the number of sex, age, there was no significant difference（P〉0.05）. In terms of course of disease, the leakage type, from the point of leakage, leakage area comparisons, the difference is statistically significant（P〈0.05）. Multivariate analysis showed that age, duration of disease, type of leakage, distance of leakage point and leakage area were the risk factors for poor prognosis of CSC（P〈0.05）. Course of disease, the type of leakage, leakage location, leakage area were positively correlated with the poor prognosis of CSC（r=0.367,0.269, 0.518, 0.325, P〈0.05）. CONCLUSION： There are many factors that lead to poor prognosis of CSC, the area, location, type and course of leakage are the risk factors of CSC prognosis.