2型糖尿病肺部改变的HRCT影像学表现及影响因素的临床研究

目的：利用HRCT评价T2DM患者肺部改变可能出现的各种影像学征象,分析其与患者临床特征的相关性.方法：收集T2DM住院病人207例,随机选择102例正常者为对照组,分析统计T2DM患者的临床特征因素与肺部异常影像的相关性.结果：①对照组胸部HRCT正常者97例,磨玻璃影2例,网织影3例;实验组胸部HRCT正常者21例,磨玻璃影33例,网织影186例;②多因素多重线性回归分析中,病程越长、并发症越多,肺部HRCT征象越严重;FC-P、餐后2hC-P值越低,肺部HRCT征象越严重.结论：①HRCT可用于T2DM患者肺部改变的评估;②病程、HbA1c、FC-P、餐后2hC-P、并发症可用来评估T2DM患者肺部改变的严重程度.

Objective：To evaluate correlations lung imaging changes of HRCT and clinical characteristics in patients of type 2 diabetes.Methods：207 cases of T2DM patients and randomly 102 cases of normal control group were selected.statistical analysis Correlation between relevant clinical characteristics of patients with T2DM and abnormality imaging findings of pulmonary.Results：① control group,102 cases of chest HRCT normal 97 cases,two cases of ground-glass opacities,reticular shadow three cases;207 cases of the experimental group of patients with normal chest HRCT 21 cases;33 cases of ground glass opacities;reticular Movies 186 cases; ②Analysis by multivariate multiple linear regression shows that the longer the duration and the more complications cause more severe lung HRCT findings.The lower fasting C-peptide and Postprandial 2 h C peptide cause the more severe lung HRCT findings.Conclusions：①HRCT can be used to assess changes in the lungs in patients with T2DM; ②duration,HbA1c,fasting C-peptide,Postprandial 2 h C peptide and complications can be used to assess the severity of pulmonary changes in patients with T2DM.