某院重度AECOPD患者病原菌分布及抗菌药物使用情况分析

目的 ：调查某院重度 AECOPD 患者病原菌分布及抗菌药物使用情况,为重度AECOPD 患者科学用药提供参考.方法：对该院呼吸科2014年10月至2015年6月收治的310例重度 AECOPD 患者的痰细菌培养及实验结果进行统计、分析.结果：阳性菌主要为真菌类,在总体菌株中占据71.47%,白色念珠菌在真菌类中占据83.33%,在全部病原菌中占据59.56%.细菌的阳性率较低,革兰阳性菌中金黄色葡萄球菌占83.33%.结论：重度 AECOPD 患者主要致病菌为真菌,临床治疗时应首先检测病原菌类型,并给予针对性抗菌治疗.

Objective： To investigate the pathogenic bacteria distribution and usage of antimicrobial agents in patients with severe AECOPD in a hospital, and to provide reference for the scientific use of patients with severe AECOPD. Methods： Three hundreds and ten cases of patients with severe AECOPD treated in our hospital from October 2014 to June 2015 were carried out sputum bacterial culture and the experiment outcomings were counted and analyzed. Results： The positive bacterium were mainly fungi, which accounted for 71.47%, and the Candida albicans accounted for 83.33% in the fungi and 59.56% in the total pathogenic bacterium. The positive of bacterium was lower, and the Staphylococcus aureus accounted for 83.33% in the Gram positive bacterium.Conclusion： The main pathogenic bacterium in patients with severe AECOPD are fungi, and the types of pathogenic bacterium should be firstly detected in the clinical treatment, and the targeted antimicrobial therapy should be given.