生长抑素联合香丹参注射液治疗重症急性胰腺炎临床研究

目的 观察生长抑素联合复方丹参注射液治疗重症急性胰腺炎（SAP）的临床疗效.方法 采用随机对照分组的临床研究方法,将2012年6月- 2016年3月收治的162例SAP患者分为对照组和观察组：对照组 （81例） 予生长抑素治疗, 治疗组 （81例） 予生长抑素联合香丹注射液治疗. 观察血清淀粉酶、 C反应蛋白、 肿瘤坏死因子和胰腺影像学变化.结果 治疗后患者临床症状、血清淀粉酶和炎症指标改善明显,治疗组和对照组的总有效率分别为98%和65%,比较差异有统计学意义（P〈0.05）.结论 生长抑素联合香丹注射液治疗重症急性胰腺炎疗效确切,临床值得推广应用.

Objective To investigate the therapeutic effect of somatostat combined with compound salvia miltlorrhiza injection on patient with severe acute pancreatitis Methods 162 SAP patients were collected and randomly divided into control group and treatment group,81 cases in each group,the former group received somatostatin therapy, the latter group was treated with somatostatin united with compound salvia miltlorrhiza injection treatment in a period from June,2012 to March,2016.The pancreatic imaging changes were observed and the serum levels of amylase（AMY）, C reactive protein（CRP） and tumornecrosis factor-a（TNF-a）were tested. Result The clinical symptoms,serum AMY,CPR and TNF-a levels and pancreatic damage were improved significantly after treatment in two groups,the total effective rate was 98% in treatment group,which was significantly different from the control group（65%,P〈0.05）.Conclusion The therapy of somatostat combined with compound salvia miltlorrhiza injection has affirmative effect on SAP patients,which should be learned by the clinicians