有创无创序贯机械通气抢救重症老年呼吸衰竭患者的有效性与安全性

Effectiveness and Safety of Invasive Noninvasive Sequential Mechanical Ven-tilation in the Treatment of Severe Respiratory Failure in Elderly Patients

目的评价有创无创序贯机械通气抢救重症老年呼吸衰竭患者的有效性与安全性。方法依据随机分组的方式将方便选取2013年2月—2015年12月份该院收治的118例重症老年呼吸衰竭患者随机分为观察组与对照组,观察组采取有创无创序贯机械通气治疗,对照组实施持续有创机械通气治疗,将两组治疗效果与治疗中患者应激反应情况作以对比分析。结果观察组Pa O2、Sa O2指标分别为(85.6±7.14)mm Hg、(96.3±3.17)%明显高于对照组,Pa CO2为(42.2±7.15)mm Hg低于对照组,差异有统计学意义(P<0.05)且E水平为(91.8±10.2)ng/m L低于对照组(P<0.05),差异有统计学意义(P<0.05)。结论有创无创序贯机械通气治疗重症老年呼吸衰竭能快速有效改善患者临床症状与体征表现,效果确切,安全可靠。

Objective To evaluate the efficacy and safety of noninvasive and invasive mechanical ventilation in the treatment of elderly patients with severe respiratory failure. Methods Convenient selection according to randomized manner in February 2013 to December 2015 118 cases of elderly patients with respiratory failure were randomly divided into observation group and control group, the observation group adopted sequential invasive noninvasive mechanical ventilation in the treatment of the control group, the implementation of continuous invasive mechanical ventilation in the treatment of patients,stress responses and treatment outcomes of the two groups for comparative analysis. Results The observation group Pa O2 and Sa O2 index respectively(85.6 ± 7.14)mm Hg、(96.3 ± 3.17)%, significantly higher than the control group, Pa CO2(42.2 ±7.15)mm Hg lower than the control group, the difference was statistically significant(P<0.05) and E level(91.8 ± 10.2)ng/m L lower than that of the control group(P<0.05), there was statistical significant difference(P<0.05). Conclusion Invasive noninvasive sequential mechanical ventilation in the treatment of severe respiratory failure in elderly patients can quickly and effectively improve the clinical symptoms and signs, the effect is exact, safe and reliable.