磁共振组织介电特性断层成像在癌症早期发现中的应用

Magnetic resonance electrical properties tomography: a new technology for early detection of tumors

基于新原理、新机制、新材料、新发现的新型成像前沿技术研究及其实现将为早期诊断、精确诊断、微创治疗、精准治疗提供核心技术支撑。"高场磁共振新成像机制-组织介电特性断层成像技术及其在临床乳腺、颅脑肿瘤诊断中的应用研究"项目获得首批国家重点研发计划项目支持,该项目将开展磁共振组织介电特性断层成像(MR EPT)技术研究,以实现无创高分辨率组织介电特性断层成像,并在临床乳腺、颅脑肿瘤诊断中开展应用研究。鉴于组织癌变后其介电特性改变较大,介电特性改变甚至达到几倍以上,MR EPT技术有望为肿瘤早期发现带来新的工程技术手段。

Cutting-edge imaging techniques based on novel principle, new mechanism, new materials, and new discovery, will provide core technical support for the early detection, accurate diagnosis, minimally invasive therapy, accurate treatment. The project titled ＂research on the new mechanism of magnetic resonance imaging--tomographic imaging of the dielectric properties of human tissues and the clinical application in the diagnosis of breast and brain tumors＂ is granted by the National Key Research and Development Program of China. In the project, the magnetic resonance electrical properties tomography （MR EPT） will be researched to realize the noninvasive dielectrical properties tomography with high resolution. And the application of MR EPT in the clinical diagnosis of breast cancer and intracranial tumor will be analyzed. Due to the prominent alteration of the dielectric properties of human tissues, even up to several folds, during the progressive process from benign to malignant status, MR EPT technique may be a promising potential tool for the early detection of tumors.