颅内真菌感染临床CT与MRI特征比较研究

Comparative study of clinical CT and MRI characteristics of intracranial fungal infection

目的探讨颅内真菌感染临床MRI和CT的影像学分析特征有利于提高疾病诊断的准确率,最大限度避免因误诊而导致的病情恶化。方法选取2008年1月-2016年12月医院经病原学确诊颅内真菌感染患者80例,通过CT和MRI影像分析其特征,总结各类颅内真菌感染病症特点。结果真菌性肉芽肿或脓肿的CT成像上多呈高密度或混杂密度,MRI扫描表现为T1W1低信号,而T2W1的信号变化大,主要呈等高或略低信号;真菌性脑膜炎广泛累及脑基底池CT成像表现为基底池密度降低,脑沟回变浅,MRI扫描表现为T2W1明显高信号,T1W1呈现等或略低信号。结论颅内肉芽肿T1W1低信号的内容物以及脑膜炎T2W1明显高信号可能是真菌感染的特征性表现。

OBJECTIVE To investigate clinical MRI and CT imaging characteristics of intracranial fungal infection to improve the accuracy of diagnosis,and maximumly avoid the deterioration caused by misdiagnosis.METHODS A total of 80 patients with intracranial fungal infection diagnosed by pathology from Jan.2008 to Dec.2016 were selected,and their characteristics were analyzed and summarized by analyzing CT and MRI imaging characteristics.RESULTS CT imaging of fungal granuloma or abscess was mostly high-density or mixed density,MRI scans showed T1W1 low signal,and the signal changes of T2W1 were large,predominantly in signal level or slightly lower.Fungal meningitis involving extensive brain base pool CT imaging showed decreased basal cell density and shallower cerebral sulcus,MRI scan showed a significantly higher signal of T2W1,and T1W1 exhibits,etc,or slightly lower signal.CONCLUSIONIntracranial granuloma T1W1 low signal content and meningitis T2W1 were significantly higher signal may be characteristic features of fungal infections.