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实时三维超声和斑点追踪技术早期评价系统性红斑狼疮患者右心房功能 被引量:10

Assessment right atrial function in patients with systemic lupus erythematosus by speckle tracking and three-dimensional echocardiography
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摘要 目的 应用实时三维超声心动图(RT–3DE)和二维斑点追踪技术(2D–STI)早期评价无肺动脉高压(PAH)的系统性红斑狼疮(SLE)患者的右心房心肌受损情况。方法 选取2011年12月—2014年5月间就诊于宁波市李惠利医院的40例临床确诊无PAH的SLE患者与40名健康对照,测量右心房整体纵向应变值(RAGLS)和各类右心房容积指数(RAVI),研究三尖瓣环位移(TAPSE)、三尖瓣环收缩期峰值S′,右心室心肌做功指数(RVMPI),ETV/e′TV等与右心房参数之间的关联。结果 SLE组的右心房最大容积指数(RAVImax)(33.5±11.1) ml/m2、右心房最小容积指数(RAVImin)(13.2±4.5) ml/m2、右心房收缩前容积指数(RAVIpre)(2.57±10.2) ml/m2、右心房主动排空容积指数(RAVIa)(12.5±7.5) ml/m2、右心房总排空容积指数(RAVIt)(20.2±8.1) ml/m2均增大,而右心房被动排空容积指数(RAVIp)(7.8±2.7) ml/m2和RAGLS(38.2%±7.7%)减低(均P〈0.05);RAGLS与S′TV、TAPSE明显正相关,r值分别为0.565与0.445 (均P〈0.01);RAVIpre、、RAVIa与ETV/e′TV明显正相关,r值分别为0.469与0.481 (均P〈0.05)。结论 应用RT–3DE和2D–STI可以早期检测无PAH的SLE患者右心房心肌受损情况,方法简便,具有明显临床价值。 Objective To evaluate right atrial function in systemic lupus erythematosus (SLE) with normal pulmonary pressure by using two dimensional-speckle tracking imaging (2D-STI) and real-time three-dimensional echocardiography(RT-3DE).Methods A totoal of 40 patients with SLE and 40 control subjects were collected between December 2011 and May 2014 from Ningbo Medical Treatment Center Lihuili Hospital. Right atrial global longitudinal strain (RAGLS) and all kinds of right atrium volume index (RAVI) were detected. Relationship between tricuspid annular plane systolic excursion(TAPSE), tricuspid annulus systolic peak velocity (S′), right ventricular myocardial performance index (RVMPI), ETV/e′TV and the right atrium parameters were analyzed.Results SLE group′s right atrium maximal volume index(RAVImax)(33.5±11.1) ml/m2, right atrium minimal volume index (RAVImin)(13.2±4.5) ml/m2, right atrium presystolic volume index (RAVIpre) (2.57±10.2) ml/m2, right atrium total emptying volume index(RAVIt)(20.2±8.1)ml/m2, right atrium active emptying volume index (RAVIa)(12.5±7.5) ml/m2) were increased .But right atrium passive emptying volume index(RAVIp)( 7.8±2.7) ml/m2 and right atrial global longitudinal strain (RAGLS) (38.2%±7.7% ) were decreased (both P〈0.05). RAGLS was positive correlated with S′ and TAPSE, the r value were 0.565 and 0.445 respectively (both P〈0.01). ETV/e′TV was positive correlated with RAVIpre, RAVIa, the r value were 0.469 and 0.481 respectively (both P〈0.05).Conclusion Detecting right atrial function by 2D-STI and RT-3DE could diagnose right atrial dysfunction in early stage of SLE patients with normal pulmonary pressure. The method is simple, has significant clinical value.
出处 《中华医学杂志》 CAS CSCD 北大核心 2016年第47期3815-3818,共4页 National Medical Journal of China
关键词 红斑狼疮 系统性 超声检查 心房功能 Lupus erythematosus, systemic,Ultrasonography,Atrial function, right
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