归脾汤加减方联合耳穴贴压疗法治疗心脾两虚型心悸的临床疗效观察

Clinical Effect of Modified Guipi Decoction Combined with Auricular Point Sticking Therapy in Treating Palpitation Patients with TCM Syndrome of Heart-spleen Deficiency

目的观察归脾汤加减方联合耳穴贴压疗法治疗心脾两虚型心悸的临床疗效。方法选择2015年1月—2016年6月就诊于广东省第二中医院心内科的心脾两虚型心悸患者72例,按就诊顺序分为对照组和治疗组,每组36例。对照组患者给予归脾汤加减方治疗,治疗组患者在对照组治疗基础上联合耳穴贴压疗法。比较两组患者临床疗效、治疗前后中医症候积分、治疗期间不良反应发生情况及停药4周后心悸复发情况。结果治疗组患者临床疗效优于对照组(P<0.05)。治疗前两组患者中医症候积分比较,差异无统计学意义(P>0.05);治疗后治疗组患者中医症候积分低于对照组(P<0.05)。治疗期间两组患者均未出现明显不良反应。停药4周后,两组患者心悸复发率比较,差异无统计学意义(P>0.05)。结论归脾汤加减方联合耳穴贴压疗法治疗心脾两虚型心悸的临床疗效确切,能有效改善患者临床症状,且安全性较高、治疗后不易复发。

Objective To observe the clinical effect of modified guipi decoction combined with auricular point sticking therapy in treating palpitation patients with TCM syndrome of heart - spleen deficiency. Methods From January 2015 to June 2016, a total of 72 palpitation patients with TCM syndrome of heart - spleen deficiency were selected in the Department of Cardiology, the Second Traditional Chinese Medicine Hospital of Guangdong Province, and they were divided into control group and treatment group according to visiting sequence, each of 36 cases. Patients of control group received modified guipi decoction, while patients of treatment group received modified guipi decoction combined with auricular point sticking therapy. Clinical effect, TCM symptoms score before and after treatment, incidence of adverse reactions during the treatment and relapse rate after 4 weeks of drug withdrawal were compared between the two groups. Results The clinical effect of treatment group was statistically significantly better than that of control group （ P 〈 0. 05 ）. No statistically significant differences of TCM symptoms score was found between the two groups before treatment （ P 〉 0. 05 ）, while TCM symptoms score of treatment group was statistically significantly lower than that of control group after treatment （ P 〈 0. 05 ）. No one of the two groups occurred any obvious adverse reactions during the treatment. No statistically significant differences of relapse rate was found between the two groups after 4 weeks of drug withdrawal （ P 〉 0. 05 ）. Conclusion Modified guipi decoction combined with auricular point sticking therapy has certain clinical effect in treating palpitation patients with TCM syndrome of heart - spleen deficiency, can effectively relive the clinical symptoms and reduce the relapse rate, with relatively high safety.