淋巴结清扫数目对淋巴结转移阴性SiewertⅡ型食管胃交界部癌的影响

Survival analysis the impact of the number of negative lymph nodes negative lymph node in Siewert Ⅱ adenocarcinoma of the esophagogastrci junction without lymphatic metastasis

目的:无淋巴结转移的SiewertⅡ型食管胃交界部癌的淋巴结清扫数目对患者预后的影响。方法:选取食管胃交界部癌根治术患者224例。对年龄、性别、肿瘤直径、肿瘤浸润深度、肿瘤分化程度、淋巴结清扫数目等因素做单因素及多因素回归分析,分析淋巴结清扫数目与患者生存率关系。结果:对各因素运用Cox回归模型分析,肿瘤分化程度和淋巴结清扫数目有统计学差异(P<0.05)。相同分化程度患者生存率随淋巴结清扫数目的增加而升高,差异有统计学意义(P<0.05)。结论:应在术中尽可能的提高淋巴结的清扫个数,从而提高患者远期生存率。

Objective To investigate the correlation between the number of resected lymph nodes and the prognosis of patients with node-negative Siewert Type II AEG. Methods Siewert Type II AEG were retrospectively assessed. The prognostic impact of the number of negative LNs and the clinic pathologic factors were analyzed. Results The same degree of the survival rate of the patients were increases with lymph nodes, the difference was statistically significant （P 〈 0.05）. Conclusion Clinicians should improve the number of lymph node dissection in the operation.