香椿树皮的亲脂性成分研究

Lipophilic constituents from the stem bark of Toona sinensis

采用硅胶、反相、凝胶柱色谱和制备薄层色谱等方法对香椿树皮95%乙醇提取物进行分离纯化,共得到10个化合物,应用光谱技术和理化常数对照等方法对其结构进行鉴定,分别为白桦脂酸(1),豆甾烷-3,6-二酮(2),豆甾-4-烯-3-酮(3),7β-羟基谷甾醇(4),6-羟基豆甾-4-烯-3-酮(5),豆甾-4-烯-3β,6β-二醇(6),过氧化麦角甾醇(7),7-methoxy-2-(3,4-methylenedioxyphenyl)benzofuran-5-carboxylat(8),铁屎米-6-酮(9),α-acetylamino-phenylpropylα-benzoylamino phenylpropionate(10)。所有化合物均为首次从该植物中分离得到。

Ten compounds were isolated from the 95% ethanol extract of the stem bark of Toona sinensis by silica gel, ODS Sephadex LH-20 column chromatographies and preparation TLC methods. Their structures were elucidated by spectroscopic methods and chemical properties as betulinic acid（1）, stigmastane-3, 6-dione（2）, stigmast-4-en-3-one（3）, 7β-hydroxysitosterol（4）, 6-hydroxystigmast-4-en-3-one（5）, stigmast-4-ene-3β, 6β-diol（6）, ergosterol peroxide（7）, 7-methoxy-2-（3, 4-methylenedioxyphenyl）benzofuran-5-carboxylate（8）, canthin-6-one（9）, and α-acetylamino-phenylpropyl α-benzoylamino phenylpropionate（10）. All compounds were isolated from T. sinensis for the first time.