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布地奈德雾化吸入治疗在COPD急性加重期的临床应用效果 被引量:3

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摘要 目的观察分析布地奈德溶液雾化吸入治疗慢性阻塞性肺疾病(COPD)急性加重期的临床效果。方法选取COPD急性加重期患者60例,随机分为观察组和对照组各30例,对照组采用解痉、针对性抗感染、纠正电解质紊乱及止咳祛痰等常规综合治疗措施,观察组在对照组治疗基础上配合布地奈德雾化吸入治疗,比较2组患者治疗前后血气指标、肺功能指标、电解质及血糖等各项指标变化情况,以及不良反应发生情况。结果治疗后2组患者血气指标、肺功能指标均较治疗前明显改善,且观察组改善情况优于对照组,差异均有统计学意义(P<0.05);2组患者电解质、空腹血糖在治疗前后比较差异无统计学意义(P>0.05),且2组之间比较差异亦无统计学意义(P>0.05);观察组发生不良反应2例,无严重全身性不良反应,对照组无不良反应发生,2组比较差异无统计学意义(P>0.05)。结论布地奈德溶液剂雾化吸入治疗COPD急性加重期可有效改善患者临床症状,控制病情,且安全性高,值得临床推广应用。
作者 万国强
出处 《临床合理用药杂志》 2016年第35期41-42,共2页 Chinese Journal of Clinical Rational Drug Use
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