神经干细胞的研究进展

The research progress of neural stem cells

神经干细胞是指能自我更新并具有分化为神经元、星形胶质细胞和少突胶质细胞,并足以提供大量神经组织细胞的一类细胞。自从90年代以来,人们相继从各种动物和人的中枢系统分离和培养出神经干细胞(neural stem cell,NSC)[1,2]。近年来,神经干细胞的发现和研究日益深入,为神经系统损伤和退行性变的治疗带来希望[3]。文章对神经干细胞来源、分离培养及鉴定方法和笔者的一些实际工作体会做一综述。

The neural stem cells are to point to self-renewal and differentiation into neurons, astrocytes and oligodendrocytes, and enough to provide a lot of nerve tissue cells. Since the nineties, people have been isolated from various animals and human central nervous system and cultivate neural stem cells.In recent years, the discovery of neural stem cells and in-depth research, for the treatment of nervous system damage and degeneration.Cultivation in this paper, the sources of neural stem cells and identifying methods and some actual work experience of the author.