脑性盐耗综合征的诊断和肾上腺皮质激素治疗的现状

The application of adrenal cortical hormone in the treatment of cerebral salt wasting syndrome

脑性盐耗综合征（CSWS）是引起顽固性低钠血症的一种常见综合征，CSWS早期准确诊断和治疗能极大促进患者病情恢复和改善预后。临床上通过补钠补水后多数患者血钠水平能恢复正常，病情缓解；而少数患者低血钠、高尿钠以及低血容量不能改善甚至加重，此类患者加用氟氢可的松等皮质激素能够快速有效降低尿钠水平和尿量，纠正低血钠症和低血容量，改善预后。

Cerebral salt wasting syndrome （CSWS） is a common cause of refractory hyponatremia. Early diagnosis and treatment of CSWS can greatly improve the patient＇s condition and improve the prognosis. Clinically by supplying sodium hydrate, most patients can resume normal serum sodium level, and get remission. But a few patients with low serum sodium, high urine sodium and low blood volume can not improve and even worse. Fludrocortisone and adrenal cortical hormone can rapidly and effectively reduce the urinary sodium level and urine volume, correct hyponatremia and low blood volume and improve the prognosis in such patients.