健康体检人群中幽门螺旋杆菌感染现状的调查及分析

Investigation on the Helicobacter pylori infection in population received health examination

目的：调查分析健康体检人群幽门螺旋杆菌（ Hp）感染状况，分析其相关的影响因素，并提出相应的对策措施。方法采用回顾分析与查阅资料的方法。选取我院2014年7月－2015年7月健康体检的南京市某社区居民150例为研究对象。体检方法为碳13-尿素呼气试验，并结合我院自制的调查问卷表格操作实施。结果①健康体检人群中Hp感染率与人群年龄分布相关。年龄愈大，Hp感染率愈低。32～45岁之间的人群Hp感染阳性率高达88．24％，46～55岁为61．90％，56～65岁为59．57％，66～75岁为54．76％，75岁以上为56．52％。②有嗜烟、酒史的人群，Hp感染率较高。在98例吸烟居民中，阳性率高达73．47％（72／98）。经常喝酒的86例中，阳性率高达80．23％（69／86）。与不吸烟和少量饮酒的人群相比，阳性率分别为26．92％和29．69％，差异有统计学意义（ P＜0．05）。③患有高血压与非高血压的人群阳性率无统计学差异。患有糖尿病、冠心病与未患糖尿病、冠心病人群比较，Hp感染率差异有统计学差异（ P＜0．05）。结论健康体检人群中Hp感染率与年龄、吸烟喝酒嗜好、慢性疾病（冠心病、糖尿病）密切相关，为指导临床Hp感染患者的治疗与预防提供了流行病学依据。

Objective Based on the practice researches of Helicobacter pylori （ Hp） infection in population received health examination, this paper was to analyze the related factors by investigating the infection status of some community residents in Nanjing, and put forward the corresponding countermeasures. Methods This paper adopted the method of retrospective analysis and information consultation. Nanjing community residents who received health examination in our hospital from July 2014 to July 2015 were selected as the research objects, among which, 150 cases were extracted. The carbon 13-urea breath test, along with our questionnaire, were observed and analysed. Results （ 1） Based on the researched objects, the HP infection rate was significantly correlated with the age distribution. The rate decreased as the age increased. Among population aged 32-45, the positive rate of HP infection was 88.24% or greater. In group aged 46-55, 56-65 and 66-75, the positive rate was 61.90%、59.57% and 54.76% respectively. While above 75 years old, the positive rate of Hp was 56.52%. （2） The HP infection rate was higher among people who had smoking or excessive drinking history. In 98 cases of smoking residents, the positive rate was 73.47% （72/98） or greater;for 86 residents drinking frequently, the positive rate was 80.23% （69/86）. Compared to the non-smoking and less-drinking group, the positive rates were 26.92% and 29.69%respectively;there was significant difference between the two groups （P〈0.05）. （3） As for population with or without hypertension, the positive rate of Hp infection was not significantly different （P〉0.05）. While for those with or without diabetes and coronary heart disease, the positive rate was significantly different （ P〈0.05） . Conclusion The result showed that the Hp infection rate was closely related with age, hobby （addicted to alcohol, tobacco, etc）, and chronic diseases （coronary heart disease, diabetes, etc）, which provides an epidemiological evidence for preventing and treating clinical HP patients.