灾害后应激性溃疡研究进展

Post-disaster stress ulcers:research progress

胃是应激状态下最为敏感的器官,其次是十二指肠。当个人遭受严重精神心理应激后,机体本能地做出功能和结构上的剧烈反应,神经、体液、炎性介质及细胞因子参与并介导胃、十二指肠黏膜发生病变,通常称之为应激性溃疡或应激性胃黏膜病变。自然灾害作为一个独特的、间接的条件使心理应激和人类消化性溃疡之间产生联系。笔者就灾后应激性溃疡的研究进展及现状作简要综述。

Stomach is the most sensitive organ to stress, followed by the duodenum. When individuals suffer severe mental stress, the body instinctively makes a functional and structural response involving nerve, body fluid, inflammatory mediators and cytokines, which causes stomach and duodenum to suffer lesion. This process is called stress ulcer or stress-related mucosal disease. As a unique, indirect factor, natural disaster links psychological stress to human peptic ulcer. The following is a brief review of the progress and status quo of the current research into post-disaster stress ulcers.