MoCA在阳江地区血管性认知障碍诊断中的临床应用研究

Clinical application of Mo CA in the diagnosis of vascular cognitive impairment in Yangjiang area

目的探讨MoCA在阳江地区血管性认知障碍诊断中的临床应用价值。方法选取阳江地区60例年龄≥65岁的血管性认知障碍的患者(痴呆组21例、非痴呆组39例)及60例年龄≥65岁认知功能正常者(对照组)为研究对象,采用MoCA量表及MMSE量表进行认知能力检测。比较两组的检测结果,分析MoCA量表的检测价值。结果痴呆组的MoCA评分、MMSE评分低于非痴呆组,非痴呆组的MoCA评分、MMSE评分低于对照组,差异有统计学意义(P<0.05)。痴呆组的MoCA评分的敏感点为90.4%,准确度为95.2%。非痴呆组为84.6%、94.9%,均高于MMSE评分,差异有统计学意义(P<0.05)。结论 MoCA在阳江地区血管性认知障碍诊断中的应用效果较好,敏感性和准确度较高,值得推广。

Objective To investigate the clinical application value of MoCA in the diagnosis of vascular cognitive impairment in Yangjiang area.Methods 60 patients with vascular cognitive impairment over 65 years old in Yangjiang area （21 cases in dementia group and 39 cases in non-dementia group）and 60 patients with normal cognitive function over 65 years old （the con-trol group）were selected as the research objects.Their cognitive abilities were tested by MoCA and MMSE scales.The results of the two groups were compared,and the application value of MoCA was analyzed.Results The MoCA scores and MMSE scores of dementia group were lower than those in non-dementia group,and the MoCA scores and MMSE scores in non-dementia group were lower than those in control group,and the differences were statistically significant （P〈0.05）.The sensitivity and accuracy of MoCA scale were 90.4% and 95.2% respectively in the dementia group,as well as 84.6% and 94.9% in non-dementia group.The sensitivity and accuracy of MoCA scale were higher than MMSE,and the differences were statistically significant （P〈0.05）.Conclusion MoCA is effective in the diagnosis of vascular cognitive impairment in Yangjiang area,and the sensi-tivity and accuracy are higher.It is worth popularizing.