尿毒症继发甲状旁腺功能亢进16例临床分析

Clinical analysis of 16 cases of hyperparathy roidism secondary to uremia

目的:探讨尿毒症继发甲状旁腺功能亢进的术前定性、定位诊断及手术治疗策略。方法:对16例尿毒症继发甲状旁腺功能亢进患者的临床资料进行总结分析。结果:除血红蛋白外,PTH、血钙、血磷、钙磷乘积术后1 d及1周呈下降趋势,术后1个月及半年后在正常范围内,随访半年,患者骨痛症状减轻,皮肤瘙痒减轻。结论:甲状旁腺次全切除对患者术后症状及实验室检查有明显的改善。

Objective： To investigate the preoperative diagnosis and surgical treatment strategy of hyperparathyroidism secondary to uremia. Methods： Summarize and analyze the diagnosis and treatment of 16 cases of hyperparathyroidism secondary to uremia with subtotal parathy roidectomy. Results： The mean level of PTH, serum calcium, phosphorus and calcium-phosphorus product was decreased after operation and maintained the normal range in the following 6 months, and the bone pain and skin itching of patients has been improved half a year later. Conclusion： Determination of PTH and parathyroid ultrasonographic has guiding effect to the surgery operation,and the symptoms of patients with SHPT can be improved through SPTX.