广东省2012年恶性肿瘤发病与死亡

Cancer Incidence and Mortality in Guangdong Province,2012

[目的]对2015年收集的广东省各肿瘤登记处上报的2012年恶性肿瘤登记资料进行分析,估计广东省恶性肿瘤的发病与死亡水平。[方法]全省共收到9个登记处上报的2012年肿瘤登记数据,通过审核和评估,共8个肿瘤登记处的数据符合入选标准。将入选的登记处按地区（城乡）、性别以及年龄别、肿瘤别发病率和死亡率分层,结合2012年全省人口数据,估计全省恶性肿瘤合计和主要肿瘤的发病、死亡情况。标化率采用全国2000年人口普查和世界Segi’s人口结构为标准。[结果 ]全省8个肿瘤登记处共覆盖登记人口15 084 942人,占全省总人口17.47%。病理诊断比例为72.84%,只有死亡证明书比例为0.87%,死亡/发病比为0.56。据估计,广东省2012年新发恶性肿瘤病例约21.1万例,死亡病例约11.7万例。全省恶性肿瘤发病率为250.20/10万（男性265.39/10万,女性234.29/10万）,中国人口标准化发病率（中标率）为207.04/10万,世界人口标化率（世标率）为201.34/10万,累积率（0~74岁）为22.91%。城市地区发病率为267.25/10万,中标率为221.43/10万,农村地区发病率为215.51/10万,中标率为178.77/10万。全省恶性肿瘤死亡率为148.44/10万（男性190.95/10万,女性105.06/10万）,中标率为103.73/10万,世标率为102.44/10万,累积率（0~74岁）为11.68%。城市地区死亡率为164.57/10万,中标率为105.46/10万,农村地区死亡率为124.63/10万,中标率99.97/10万。肺癌、肝癌、女性乳腺癌、结肠癌和鼻咽癌是广东省恶性肿瘤发病的前5位,肺癌、肝癌、结肠癌、胃癌和鼻咽癌是前5位的肿瘤死因。[结论]肺癌、肝癌、结肠癌、女性乳腺癌以及鼻咽癌的疾病负担沉重,是威胁居民健康的主要恶性肿瘤。在肿瘤防控工作中,针对不同癌种进行早预防,早期发现,早期治疗,提高生存质量,减轻疾病负担是我们面临的重要问题。

[Purpose] To estimate the cancer incidence and mortality in 2012 in Guangdong province by analyzing the cancer data of selected population-based cancer registries in Guangdong province. [Methods] Cancer data were submitted from 8 of 9 population cancer registries to the Guangdong Provincial Centre for Disease Control and Prevention（Guangdong CDC）,and the data from 8 registries met the quality criteria were included for analysis. The qualified data were stratified by areas,gender,age and cancer types to estimate the cancer incidence and mortality in 2012 in Guangdong province. Segi＇s population and the national census population in 2000 were used for calculating the age-standardized rate（ASR）. [Results] The 8 selected population-based cancer registries covered 15 084 942 residents,accounted for 17.47 percent of all population in Guangdong province in 2012. Of all cancer cases 72.84% and 0.87% were confirmed by MV（microscopic verification） and DCO（death certificate only）,respectively,and the mortality/incidence（ M/I） ratio was 0.56. It was estimated that there were 211 300 cancer new cases and 117 300 deaths. The incident crude rate（CR）,ASR for China and world（ASR-China and ASR-world） and accumulated rate（AR）（ 0 ~74 years） were 250.20/105（male 265.39/105,female 234.29/105）,207.04/105,201.34/105,and 22.91%,respectively in Guangdong in 2012. The incidence CR and ASR-China in urban areas were 267.25/105 and 221.43/105,respectively,215.51/105 and 178.77/105 in rural areas,respectively. The death CR,ASR-China,ASR-world,and AR（ 0~74 years） were 148.44/105（male190.95/105,female 105.06/105）,103.73/105,102.44/105,and 11.68%,respectively. The death CR and ASR-China in urban areas were 164.57/105 and 105.46/105,respectively,124.63/105and99.97/105 in rural areas,respectively. Top 5 incident cancers were lung,liver,female breast,colon,and nasopharyngeal cancers（NPC）,and top 5 death cancers were lung,liver,colon,stomach,and NPC in Guangdong in 2012. [Conclusions] Lung,liver,female breast,colon,and NPC are the major cancer burden and health concerns in Guangdong in 2012. Early prevention,diagnosis and treatment as well as,improving its survival quality and reducing cancer burden are the important issues in cancer control and prevention work.