摘要
目的:研究对比采用依那普利和硝苯地平治疗高血压的临床效果。方法:选取2014年3月至2015年3月在丰城段潭卫生院接受治疗的高血压患者80例,按不同的用药方式将其分为硝苯地平组(X组)和依普利钠联合硝苯地平组(L组),各组40例,硝苯地平组(X组)患者给予硝苯地平口服治疗,依那普利和硝苯地平组(L组)采用两者联合的治疗方法,观察两组的治疗效果和血压下降情况。结果:L组的总有效率96.5%明显高于X组的总有效率87.7%,治疗后Y组和L组的血压均下降,但L组的下降更明显,对比后两组差异显著P<0.05,具有可比性。结论:依那普利和硝苯地平治疗高血压具有比较明显的效果,无显著不良反应,值得临床推广使用。
Objective: Comparative study to explore the clinical effect of enalapril and nifedipine in the treatment of hypertension.Methods: 80 cases hypertension from March 2014 to March 2015 in Fengcheng Duantan Institutes for treatment were divided into nifedipine group (X group) and sodium eplerenone joint nifedipine group (L), each group has 40 patients. Nifedipine group (X group) was treated with oral nifedipine treatment, nifedipine and enalapril group (L) using the combination of the two methods of treatment, therapeutic effect and blood pressure conditions were observed.Results: The total effective rate of 96.5% L group was significantly higher than the X group total effective rate 87.7%, and blood pressure after treatment group Y L group decreased, but the decline is more pronounced L group (P〈0.05).Conclusion: Enalapril and nifedipine treatment of hypertension has obvious effect, no significant adverse reactions, thus it is worthy of clinical use.
作者
李永清
LI Yong-qing(Fengcheng Duantan Institutes, Fengcheng Jiangxi 331129, China)
出处
《药品评价》
CAS
2016年第19期51-52,64,共3页
Drug Evaluation