山东省高青县医院健康体检人群的血脂状况研究

The blood lipid status study of the healthy check -up crowd in the People＆#39;s Hospital of Gaoqing county, Shandong province

目的：了解山东省高青县医院健康体检人群的血脂状况及其影响因素，为建立健康的生活方式提供重要的理论依据。方法前瞻性地选取2013年9月至2015年8月367例在高青县医院体检人群为研究对象，用全自动生化分析仪来检测所选研究对象血清中总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）、载脂蛋白 A（ApoA）及载脂蛋白 B（ApoB）的浓度，然后按研究对象的年龄、性别及可能的危险因素进行分组并将所检测的结果并进行统计分析。结果 TC、TG、HDL-C、LDL-C 及 ApoB 随着年龄的增长均有增加的趋势（F ＝48．121、51．343、46．873、47．342、12．865、53．012，均 P ＜0．05）；TC、HDL-C 及 ApoA 在女性研究对象血清中的水平均明显高于男性（t ＝2．143、1．669、0．979，均 P ＜0．05），而 TG 的水平明显低于男性（t ＝2．143，P ＜0．05）；脑力劳动人群血清的 TC、HDL-C 及 ApoA 水平明显高于进行体力劳动的人群（t ＝2．056、5．721、2．029，均 P ＜0．05）；TC、TG、LDL-C 及 ApoB 在血清中的水平随着体质指数（BMI）的增加有逐渐增加的趋势（F ＝3．142、7．355、6．622、5．012，均 P ＜0．05），而 HDL-C 及 ApoA在学清中的水平随着 BMI 的增加而有逐渐减少的趋势（F ＝4．379、73．865，均 P ＜0．05）。结论高青县医院健康体检人群存在高脂血症状况，特别要注意老年、女性、脑力劳动及 BMI 高的人群的血脂。

Objective To know the blood lipid status and its influencing factors of the healthy check -up crowd in the People＇s Hospital of Gaoqing County,Shandong,and to provide theoretical basis for a healthy lifestyle. Methods 367 cases for medical health examination were collected as the study subjects from September 2013 to August 2015 in our hospital.The concentrations of total cholesterol（TC）,triglyceride（TG）,high -density lipoprotein cholesterol（HDL -C）,low density lipoprotein cholesterol（LDL -C）,apolipoprotein A（ApoA）and apolipoprotein B （ApoB）in serum of the study subjects were detected with automatic biochemical analyzer.And then,the study sub-jects were grouped according to the age,gender and the possible risk factors.The results were analyzed.Results The concentrations of TC,TG,HDL -C,LDL -C and ApoB had increasing trends with age（F =48.121,51.343,46.873, 47.342,12.865,53.012,all P 〈0.05）.The levels of TC,HDL -C and ApoA in serum of women were significantly higher than those in men（t =2.143,1.669,0.979,all P 〈0.05）.The levels of TC,HDL -C and ApoA in serum of knowledge workers were significantly higher than the manual workers（t =2.143,P 〈0.05）.TC,TG,LDL -C and ApoB had the trends of increase gradually with the increase of the body mass index（BMI）（F =3.142,7.355,6.622, 5.012,all P 〈0.05 ）.HDL -C and ApoA had the trends of reduce gradually with the increase of the BMI（F =4.379,73.865,all P 〈0.05）.Conclusion There is hyperliplidemia conditions in the health check -up crowd in the People＇s Hospital of Gaoqing County,especially in the elderly,women,mental workers,and the high BMI should be pay more attention.