悬雍垂腭咽成形术后多模式镇痛临床研究

Clinical study of multimodal analgesia for uvulopalatopharyngoplasty

目的探讨悬雍垂腭咽成形术(UPPP)后多模式镇痛方法的选择及效果。方法回顾性分析2015年7月至2016年6月中国医科大学附属第一医院行UPPP患者78例,其中,术后应用酒石酸布托啡诺的患者35例设为布托啡诺组,行自控静脉镇痛(PCIA)的患者43例设为PCIA组。比较两组患者术后镇痛相关并发症发生率、术后72 h疼痛评分。结果两组患者术后72 h镇痛效果比较,差异无统计学意义(P>0.05);但布托啡诺组术后镇痛相关并发症发生率明显低于PCIA组,两组间比较,差异有统计学意义(P<0.05)。结论两种术后镇痛方式均可提供有效、稳定的术后镇痛效果,但使用酒石酸布托啡诺镇痛的并发症发生率更低,具有更高的安全性。

Objective To explore the application and the effectiveness of postoperative multimodal analgesia for uvulopalatopharyngoplasty（ UPPP）. Methods A retrospective study was performed on 78 patients underwent UPPP in the First Hospital of China Medical University from July 2015 to June 2016. Patiens were divided into the butorphanol（ butorphanol tartrate） group（ n = 35） and PCIA（ patient controlled analgesia） group（ n = 43）. The visual analogue score and the incidence of postoperative analgesia related complications in the first postoperative 72 hours between the two groups were compared. Results The analgesic effect of the two groups was almost the same（ P 0. 05）. The incidence of postoperative analgesia related complications in PCIA group is higher,the difference was statistically significant（ P 0. 05）. Conclusion Both kinds of postoperative analgesia are effective. Butorphanol tartrate has lower incidence of complications,and it is safe for clinical application.