卫喜康改善膀胱灌注后药物保留时间过短的可行性研究

The research of the feasibility of improving too short drug retention time after bladder perfusion with Vesicare

目的探讨卫喜康改善膀胱灌注后药物保留时间过短的可行性。方法对44例膀胱肿瘤电切术后行膀胱灌注,发生尿频尿急等,药物保留困难,药物明显外漏,在常规处理基础上,药物保留时间仍不到15分钟的病例,口服卫喜康一周,再次灌注,比较小便次数、尿急、尿失禁、保留时间及满意度情况。结果患者治疗前后膀胱灌注OABSS评分、保留时间、满意度等方面,差别均有统计学意义(均P<0.01)。结论对膀胱肿瘤术后膀胱灌注药物保留时间过短的患者,在常规处理效果不佳的情况下,口服卫喜康可以改善大部分患者的尿频尿急,增加膀胱灌注药物保留时间,提高疗效及满意度。

Objective Try to research the feasibility of Vesicare which improving too short drug retention time after bladder chemotherapy drugs perfusion.Methods Include 44 cases postoperative bladder tumor patients who can＇t tolerate procedure of bladder perfusion and liquid retention time less than 15 minutes after routing treatment.These patients take oral Vesicare one week before next bladder perfusion.Compare their OABSS,times of drug retention,satisfaction degree recorded after with before get oral drugs.Results There are statistic differences in OABSS,retention time of bladder perfusion,satisfaction degree after take oral drugs（P〈0.05）.Conclusion If it is too short about drug retention of postoperative bladder perfusion patients＇ time,Vesicare for one week before next procedure should improve the retention time of most patients;also get better effect and satisfaction,in the case of no expected effect by regular treatment.