摘要
目的探讨血脂分析中低密度脂蛋白胆固醇异常对视网膜中央动脉阻塞（CRAO）患者的临床意义。方法选择2012年1月至2014年12月CRAO患者12例为观察组，同期选择无眼部症状及全身不适的12例健康体检者为对照组。患者化验检查血液血脂分析，包含血清总胆固醇（TC），血清甘油三酯（TG），高密度脂蛋白胆固醇（HDL-C），低密度脂蛋白胆固醇（LDL．C）以及颈动脉血管彩色多普勒超声检查粥样斑块形成。应用SPSS17．0统计软件进行数据分析，对LDL-C及颈动脉粥样斑块发生率进行比较。结果观察组12例CRAO患者中，有LDL-C增高6例（50．0％），TC增高1例（8．3％），TG增高3例（25．0％），HDL—C降低1例（8．3％），颈动脉血管彩色多普勒超声检查，颈动脉粥样斑块7例（58．3％）。对照组中，LDL—C增高0例，Tc增高1例（8．33％），TG增高1例（8．33％），HDL-C降低0例（0％），颈动脉血管彩色多普勒超声检查，颈动脉粥样斑块2例（16．7％）。观察组LDL—C增高以及颈动脉粥样斑块发生率明显高于对照组，差异有统计学意义（P〈0．05）。结论血脂分析中LDL—C与CRAO的发生有密切关系，是CRAO及颈动脉粥样斑块形成的危险因素。
Objective To investigate the chnical significance of low density lipoprotein choles- terol abnormalities in the patients with central retinal artery occlusion. Methods Twelve patients （ 12 eyes） with central retinal artery occlusion（CRAO） between January 2012 and December 2014 were selected as the research objects. Proceeded blood liqid and color doppler ultrasonography examination, in- cluding serum total cholesterol （ TC ）, triglycerides （ TG ）, high-density lipoprotein cholesterol （ HDL-C ）, low density lipoprotein cholesterol （LDL-C）, common carotid artery intima-media thickness carotid plaques were detected. The low density lipoprotein cholesterol（LDL-C） were compared. Results LDL-C increased in 6 cases （50. 0% ）, TC increased in 1 cases（8.33% ）, TG increased in 3 cases （25.0%）, Carotid atherosclerotic plaque were found in 6 cases （50. 0% ）. In control group, LDL-C increased in 0 case （0. 0% ）, TC increased in 1 case （8.33%）, TG increased in 1 case （8.33%） ,Carotid atheroscle-rotic plaque were found in 2 cases（ 16.7% ）. The incidence of LDL-C and carotid atherosclerotic plaque in CRAO group were significantly higher than the control group, and the difference was significant （P 〈 0. 05）. Conclusions LDL-C and carotid artery change is closely correlated with the pathogenesis of CRAO, and is the risk factors of CRAO and carotid atherosclerotic plaque development.
出处
《中国实用医刊》
2016年第23期97-99,共3页
Chinese Journal of Practical Medicine
