输血治疗前使用不规则抗体检验的临床意义和价值

Clinical significance and value of unexpected antibody test before blood transfusion therapy

目的研究输血前检验意外抗体的临床价值与意义。方法选择2014年8月至2016年8月我院收治的120例受血者为研究对象,将其分为试验组、参照组,试验组62例,参照组58例。在参照组接受输血治疗之前,仅检验血清中的抗-A及抗-B,对于试验组的62例受血者,输血前同时检验了抗-A、抗-B及意外抗体。结果试验组中9例受血者的意外抗体检验结果呈阳性,阳性率为14.52%;抗体类型包括抗-E 3例,抗-C 1例,抗-D 3例,抗-M 2例。试验组受血者输血反应发生率为9.68%,参照组为24.14%,参照组输血反应发生率显著高于试验组。结论在实施输血治疗之前检验意外抗体,可避免延误临床救治,并可降低输血反应的发生率。

Objective To study the clinical value and significance of unexpected antibody test before blood transfusion therapy. Methods One hundred and twenty patients admitted from August 2014 to August 2016 in our hospital were included in this study. All patients were divided into the test group （n=62） and the reference group （n=58）. For the reference group, only anti-A and anti-B in serum were tested before blood transfusion; for the test group, anti-A, anti-B and unexpected antibody were tested before blood transfusion. Results The test result of nine blood recipients in the test group showed unexpected antibody, with the positive rate of 14.52%. The antibody type included 3 cases of anti-E, 1 case of anti-C, 3 cases of anti-D and 2 cases of anti-M. The incidence of blood transfusion reaction in the test group and the reference group was respectively 9.68% and 24.14%. The incidence rate of the reference group was significantly higher than that of the test group. Conclusion Unexpected antibody test before blood transfusion therapy may avoid clinical treatment delay and reduce the incidence of blood transfusion reaction.