DTI技术定量测量健康成人髌软骨的初步研究

Preliminary study of diffusion tensor imaging in quantitative measurement of normal adult patella cartilage

目的:探讨3.0T磁共振扩散张量成像(DTI)定量测量正常髌软骨的可行性。方法:对40例健康青年志愿者的右膝关节髌软骨进行DTI扫描,利用Matlab 7.1及Mricron应用软件对图像进行后处理,观察髌软骨的DTI表现,并测量其表观扩散系数(ADC)及各项异性分数(FA)值。结果:40例中仅4例图像质量较差。髌软骨的ADC及FA图表现均表现为沿髌骨表面走行的稍高信号,其ADC值为(1.428±0.087)×10-3 mm2/s,FA值为0.207±0.018。结论:3.0T磁共振能进行髌软骨DTI,其定量测量参数能反映髌软骨的水分子扩散特征。

Objective：To study the feasibility of quantitative measurement of normal adult patella cartilage using diffusion tensor imaging （DTI） at 3.0T MR system. Methods：40 healthy young volunteers were included in this study. Each of the right patellar cartilage was scanned by DTI sequence,and the image data were post--processed using the Matlab 7.1 and Mricron software,the values of apparent diffusion coefficient （ADC） and fractional anisotropy （FA） of patella cartilage were measured. Results：On patella cartilage images of 40 cases, there were only 4 cases with poor image quality. On ADC and FA images, the patella cartilages all showed relative high signal intensity along the surface of the patella. The values of ADC were （1. 428 ± 0. 087） × 10^-3 mm^2/s, the values of FA were 0. 207±0.018. Conclusion ： Patella cartilage can be clearly showed by diffusion tensor imaging （DTI） at 3.0T MR system; DTI quantitative measurement can precisely reflect water molecules diffusion characteristics in normal adult patella cartilage.