隐孢子虫实验室安全风险评估模型的建立

Establishment of a risk assessment model for laboratory biosafety of Cryptosporidium

目的建立隐孢子虫实验室安全风险评估模型,为从事隐孢子虫相关操作的实验室人员做好安全工作和预防实验室内发生隐孢子虫感染提供依据。方法通过查阅文献和德尔菲法确定隐孢子虫实验室感染发生的风险因素,然后通过模糊层次分析法确定风险因素的权重,建立隐孢子虫实验室安全风险评估模型。结果建立了隐孢子虫实验室安全风险评估模型,各风险指标中粪便样本处理发生隐孢子虫实验室感染的概率较高,且危害程度高,其发生可能性、危害程度的指标组合权重分别为0.111和0.107,属于高危风险因素。结论本研究建立的隐孢子虫实验室安全风险评估模型具有可行性,可望为实验室人员做好相应防护措施、预防实验室内发生隐孢子虫感染发生提供依据。

Objective To evaluate the risk assessment model of Cryptosporidium laboratory,so as to provide the basis for laboratory personnel engaging in the operation of Cryptosporidium. Methods Firstly,the risk factors of Cryptosporidium infec？tion in laboratory were determined by the literature and Delphi,and then the weights of risk factors were determined by fuzzy an？alytic hierarchy process. A risk assessment model for laboratory biosafety of Cryptosporidium was established. Results Com？pared to the indexes,based on the risk assessment model,stool sample processing was the two steps in the laboratory with high risk of infection and high risk factors,with the combination weights of risk possibility and hazard rating were 0.111 and 0.107, respectively. Conclusion The risk assessment model established is feasible. It can be used to make some suggestions for the re？lated laboratory staff.