腹腔镜胆囊切除术与根治性切除术治疗早期胆囊癌的疗效对比

Comparison of the Curative Effect Between Laparoscopic Cholecystectomy and Radical Cholecystectomy in the Treatment of Early Gallbladder Carcinoma

目的对比腹腔镜胆囊切除术与根治性胆囊切除术治疗早期胆囊癌的临床疗效。方法选取我院就诊的126例早期胆囊癌患者,随机分为观察组(腹腔镜胆囊切除术)和对照组(根治性胆囊切除术),每组各63例,对比两组临床疗效。结果观察组术中出血量、手术时间、术后胃肠功能恢复时间、术后排气时间和住院时间短于对照组(P<0.05)。观察组并发症发生率低于对照组(P<0.05)。观察组术后1年胆囊癌复发率高于对照组(P<0.05)。结论腹腔镜胆囊切除术治疗早期胆囊癌具有明显手术优势,但根治性胆囊切除术复发率较低,因此,临床应根据患者实际病情及癌细胞转移倾向选择合适的手术方式。

Objective To compare the clinical effect of laparoscopic cholecystectomy and radical cholecystectomy in the treatment of early gallbladder carcinoma. Methods 126 cases of patients with early gallbladder carcinoma were randomly divided into observation group（laparoscopic cholecystectomy）and control group（radical cholecystectomy）in our hospital,63 cases of patients in each group. The clinical efficacy between two groups was compared. Results The bleeding volume,operation time,postoperative recovery time,exhaust time and hospitalization time of the observation group were significantly shorter than that of the control group（P〈0.05）. The incidence of complications in the observation group was significantly lower than that in the control group（P〈0.05）. The recurrence rate of gallbladder carcinoma in the observation group was significantly higher than that in the control group（P〈0.05）. Conclusion Laparoscopic cholecystectomy in the treatment of early gallbladder carcinoma has obvious advantages,but the recurrence rate of radical cholecystectomy is low,therefore,the clinical treatment should be based on the actual condition of the patient and the tendency of cancer cell metastasis to choose the appropriate operation mode.