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宫颈癌根治术联合化疗对患者术后生存质量的影响 被引量:1

Combination Chemotherapy of Cervical Cancer Radical Impact on the Quality of Patients With Postoperative Survival
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摘要 目的 探讨宫颈癌根治术联合化疗对患者术后生存质量的影响。方法 选取我院2014年9月~2016年7月收治的96例宫颈癌患者为研究对象,将所有患者按照不同的治疗方法分为对照组和研究组。每组48例,对照组患者仅行宫颈癌根治术,研究组在对照组的基础上联合新辅助化疗,对比两组患者的手术效果。结果 研究组患者的缓解率高于对照组,两组比较差异有统计学意义(P〈0.05)。研究组术后并发症发生率低于对照组,两组比较差异有统计学意义(P〈0.05),研究组淋巴结阳性率、宫旁累及阳性率以及阴道切缘阳性率低于对照组,两组比较差异有统计学意义(P〈0.05)。结论 术前新辅助化疗联合宫颈癌根治术能有效提高患者的生存质量,减少术后并发症。 Objective To explore combination chemotherapy of cervical cancer radical impact on the quality of patients with postoperative survival. Methods 96 cases of patients with Cervical cancer were seclected from September 2014 to July 2016, divided them into the study group and the control group, 48 cases in each group, the control group patients were given cervical cancer radical treatment, and patients in the control group based on the study group to chemotherapy, compare the surgical effect of two groups of patient. Results Remission rate of the study group was signficantly higher than the control group, the difference was statistically sigaaifieant ( P 〈 0.05 ) . The study group was incidence of complications were sigaaificantly lower than the control group, the difference was statistically significant ( P 〈 0.05 ), the study group lymph node positive rate and near the palace iuvolvemem positive rate and vaginal cut edge positive rate, the difference was statistically sigmificant (P 〈 0.05 ) . Conclusion Preoperative neoadjnvant chemotherapy joint can effectively improve the quality of survival in patients with cervical cancer radical, to reduce the postoperative complications.
出处 《中国卫生标准管理》 2016年第23期32-33,共2页 China Health Standard Management
关键词 宫颈癌根治术 化疗 生存质量 术后并发症 Cervical cancer radical, Chemotherapy, Quality of life, Postoperative complications
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  • 1赵玉梅,陈俊,陈莉莉.术前新辅助化疗对ⅠB2~ⅡB期宫颈癌的近期疗效观察[J].肿瘤防治研究,2008,35(S1):24-25. 被引量:13
  • 2万崇华,陈明清,张灿珍,汤学良,孟琼,张晓磬.癌症患者生命质量测定量表EORTC QLQ-C30中文版评介[J].实用肿瘤杂志,2005,20(4):353-355. 被引量:1304
  • 3程晓东,谢幸,吕卫国.局部晚期宫颈癌新辅助化疗临床应用的进展[J].中华医学杂志,2005,85(30):2154-2156. 被引量:31
  • 4吕娟,刘志鹏.子宫颈癌的新辅助化疗[J].中国妇幼保健,2007,22(12):1704-1706. 被引量:15
  • 5Tiemey J. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials[ J]. Eur J Cancer, 2003,39 ( 17 ) : 2470 - 2486.
  • 6Duenas-Gonzalez A, Lopez-Graniel C, Gonzalez-Enciso A, et al. Concomitant chemoradiation versus neoadjuvant chemotherapy inlocally advanced cervical carcinoma: results from two consecutive phase II studies[J]. Ann Oncol ,2002,13(8) :1212 - 1219.
  • 7Buda A, Fossati R, Colombo N, et al. Randomized trial of neoadjuvant chemotherapy comparing paclitaxel, ifosfamide, and cisplatin with ifosfamide and cisplatin followed by radical surgery in patients with locally advanced squamous cell cervical carcinoma: the SNAP01 ( Studio Neo-Adjuvante Portio ) Italian Collaborative Study [ J ]. J Clin Oncol, 2005,23(18) : 4137 -4145.
  • 8Kuo DY, Blank SV, Christo PJ, et al. Paclitaxel plus oxaliplatin for recurrent or metastatic cervical cancer: A new york cancer consortium study[J]. Gynecol Oncol, 2010, 116(3) : 442 -454.
  • 9Kelland LR. Meeting report on 8th international symposium on platinum and other metal coordination in cancer chemotherapy [ J]. J Inorg Biochem,1999,77( 1 -2) :121 -124.
  • 10Kim YS, Hong J, Sym S J, et al. Oxaliplatin, 5-fluorouracil and leucovorin (FOLFOX-4) combination chemotherapy as a salvage treatment in advanced gastric cancer [ J]. Cancer Res Treat ,2010, 42 ( 1 ) :24 -29.

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