厄洛替尼治疗晚期非小细胞肺癌的临床研究

The Clinical Research of Erlotinib in Treatment of Advanced Non-small Cell Lung Cancer

目的 探讨分析晚期非小细胞肺癌患者接受厄洛替尼治疗的临床效果,为临床中的治疗提供可靠的参考信息。方法 根据2012年12月~2014年12月我院的30例晚期非小细胞肺癌患者进行研究分析,使用厄洛替尼治疗,患者接受药物治疗后,对其毒副反应以及效果进行观察分析。结果 全部患者中有10例疾病进展,13例病情稳定,6例部分缓解,1例完全缓解,7例治疗有效。患者接受药物治疗后有皮疹、皮肤瘙痒、腹泻、恶心等毒副反应,均不严重,针对性的采取治疗措施后,均得到了缓解。结论 晚期非小细胞肺癌患者接受厄洛替尼治疗的临床效果突出,可能会出现较轻的毒副作用,但是针对性处理后可以缓解,均不严重。

Objective To investigate the clinical effect of advanced non receive erlotinib in patients with small cell hmg cancer, to provide a reliable reference infurmation for the clinical treatment. Methods According to the 30 cases from December 21112 to December 2014 in our hospital were stndied in patients with non sman cellhmg cancer, the use of erlotinib treatment, patients received drug treatment, obserwtion and analysis were carried out on the toxicity and etTect. Results There were 10 cases of disease progression in all patients, stable in 13 cases, partial remission in 6 cases, complete remission in 1 case, and effective treatment in 7 cases. Patients received drug treatment rash, skin itching, diarrhea, nausea and other side effects, are not serious, targeted to take treatment measures, have been alleviated. Conclusion Advanced non clinical effect to receive erlotinib in patieuts with small cell hmg cancer is promineut, there may be less side effects, but the treatment cau alleviate, not serious.