急性髓系白血病化疗后骨髓抑制层流床应用的临床观察

Clinical Observation of Application of Myelosuppression Laminar Flow-beds on Patients with Acute Myeloid Leukemia after Chemotherapy

目的:探讨急性髓系白血病患者化疗后出现骨髓抑制层流床预防医院感染的效果。方法:选择2014年7月~2016年3月急性髓系白血病化疗后出现骨髓抑制50例,随机分为观察组和对照组,每组25例。两组均予常规治疗与护理,观察组在此基础上入住层流床,对照组住普通病室。观察两组医院感染率、抗生素使用天数、发热持续时间和住院天数。结果:观察组医院感染率低于对照组,抗生素使用天数,发热持续时间和住院天数均短于对照组(P<0.01,P<0.05)。结论:急性髓系白血病患者化疗后骨髓抑制期住层流床能显著降低院感的发生率,提高病床周转率,缩短住院时间。

Objective：To investigate the effect of laminar flow-beds in the prevention of nosocomial infection on patients with acute myeloid leukemia （AML） and bone marrow depression after chemotherapy.Methods：50 cases of patients with AML and bone marrow depression after chemotherapy from July 2014 to March 2016 were selected and randomly divided into observation group （n = 25） and control group （n = 25）.Based on conventional therapy and nursing care, patients in observation group lay in laminar flow-beds, and then patients in control group lived in ordinary wards.Then the nosocomial infection rate, antibiotic use daYs, duration of fever,and the hospital stay of two groups were observed.Results：The nosocomial infection rate, duration of fever, days of antibiotics use and the hospital days of observation group were significantly better than those of control group （P〈0.01, P〈0.05）.Conclusion： Patients with AML in bone marrow depression period after chemotherapy lying in laminar flow-beds can reduce incidence of nosocomial infection and shorten hospital stay.