桂林市某医院体检中心成年人血脂异常流行病学调查及其危险因素分析

Epidemiological survey on and risk factor analysis of dyslipidemia among adults in a hospital in Guilin

目的 了解桂林市成年人血脂异常患病情况,并分析其主要的危险因素。方法 对桂林市6 660名成年人进行体格测量、实验室检查和肝脏彩超检查等。结果 6 660名成年人血脂异常患病率为31.8%（男性为40.5%,女性为22.3%）,标化后患病率为30.6%（男性为39.9%,女性为27.0%）;高TC、高TG、高LDL-C、低HDL-C患病率分别为8.0%、17.0%、13.8%、13.3%;血脂异常患病率以男性40~49岁年龄段最高,呈随年龄的增加患病率先逐渐增加后降低趋势,女性则随着年龄的增加而显著升高。血脂异常组合并高血糖、高血压、超重和（或）肥胖、非酒精性脂肪肝（NAFLD）、高尿酸血症的患病率均高于正常组（P〈0.05）。多因素logistic回归分析显示：性别（男）、年龄、体重指数（BMI）、NAFLD、高尿酸血症、高血糖均为血脂异常的危险因素。结论 桂林市成年人血脂异常患病率较高,男性、年龄、BMI、NAFLD、高尿酸血症、高血糖均为血脂异常的危险因素。

Objective To investigate the prevalence of dyslipidemia among aduhs in Guilin, and to analyze the common risk factors for dyslipidemia. Methods A total of 6 660 adults were cross-sectionally investigated, mainly including physical examination, laboratory examination and liver color Doppler ultrasound examination. Results The crude prevalence rate of dyslipidemia among 6 660 adults in Guilin was 31.8 % （ male ： 40.5 % , female ： 22.3 % ） and the standardized prevalence rate was 30.6 % （ male ： 39.9 % , female ： 27.0% ）. Prevalence rates of high TC, high TG, high LDL-C and low HDL-C levels among adults in Guilin were 8.0% , 17.0% , 13.8% and 13.3% respectively. In male, the highest prevalence rate of dyslipidemia was observed in the 40 - 49 year bracket group, and the prevalence rate first increased gradually and then decreased with the increasing age, while in female, the prevalence rate of dyslipidemia increased significantly with the increasing age. The prevalence rates of patients in the dyslipidemia group who complicated with hyperglycemia, hypertension,overweight and（or） obesity,non-alcoholic fatty liver disease（NAFLD） ,hyperuricemia were significantly higher than those of normal group （ P 〈 0.05 ）. Multivariate logistic regression analysis revealed that male, age, body mass index （ BMI ）, NAFLD, hyperuricemia and hyperglycemia were risk factors for dyslipidemia. Conclusion The prevalence rate of dyslipidemia is high among adults in Guilin. Male, age, BMI, NAFLD, hyperuricemia and hyperglycemia are risk factors for dyslipidemia.