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性激素结合球蛋白与胰岛素抵抗相关性疾病关系的研究进展 被引量:16

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摘要 性激素结合球蛋白(SHBG)是来源于肝脏的一种结合性激素的糖蛋白,不仅是一种运载蛋白,而且还具有激素样作用,与受体结合后可参与类固醇激素的信号转导过程。研究证实血浆SHBG水平与机体胰岛素抵抗(IR)程度有关,并参与2型糖尿病、妊娠期糖尿病、多囊卵巢综合征、高尿酸血症、非酒精性脂肪肝、肥胖、肿瘤等IR相关性疾病的发生。
作者 刘英 江霞
出处 《山东医药》 CAS 北大核心 2016年第46期105-107,共3页 Shandong Medical Journal
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