苦黄散治疗普通型手足口病肺脾湿热证临床研究

Clinical Study of Kuhuangsan in Treating normal type of Hand,Foot and Mouth Disease with Lung-Spleen Dampness-Heat Syndrome

目的探讨苦黄散外洗对肺脾湿热型小儿普通型手足口病的治疗效果。方法选取我院诊治的肺脾湿热型小儿普通型手足口病患儿80例,随机分为对照组和观察组,其中对照组采取单磷酸阿糖腺苷等抗病毒治疗,观察组在对照组的基础上给予苦黄散外洗,观察两组患儿的病情恢复情况,并从体温复常时间、皮疹消退时间、症状改善等方面对治疗效果进行评价。结果观察组有效率为92.50%,对照组为70.00%,两组比较差异具有统计学意义P<0.05;观察组体温复常时间为(3.34±1.56)天,明显少于对照组的(5.45±2.43)天,差异有统计学意义(P<0.05);观察组皮疹消退时间为(6.12±1.69)天,与对照组的(10.38±2.25)天比较,差异有统计学意义(P<0.05)。结论在西医治疗的基础上,使用苦黄散外洗治疗小儿普通型手足口病,可提高临床疗效,缩短发热时间,加快皮疹消退,有效促进患儿康复。

Objective To explore the effect of external application of Kuhuangsan on the treatment of normal type of children hand,foot and mouth disease with lung-spleen damp-heat. Methods Eighty children with normal type of children hand, foot and mouth disease were randomly divided into the control group and observation group. The control group was treated with antiviral drugs such as adenosine monophosphate,while the observation group was treated with Kuhuangsan, and the recovery rate of the two groups was observed. The treatment effect was evaluated from body temperature,rash subsided and the improvement of symptoms. Results The effective rates of the two groups were 92.50% and 70.00% in the observation group and control group respectively（P〈0. 05）. The time of body temperature recovery in observation group（3.34±1.56） was significantly less than control group（5.45±2.43）days（P〈0.05）. The rash subsided time of observation group （6. 12±1.69）day swas significantly less than control group （10.38±2.25）days （P〈0. 05）. Conclusion On the basis of western medicine treatment, the treatment of normal type of children hand, foot and mouth disease by using Kuhuangsan can improve the clinical curative effect, shorten the fever time, accelerate the rash subsided, shorten the course of disease and save the medical expenses.