江苏省扬州地区 41 例非结核分枝杆菌肺病的流行病学及临床特征分析

Epidemiological and clinical features of 41 cases with non tuberculosis mycobacterium pulmonary disease in Yangzhou,Jiangsu Province

目的 探讨扬州地区非结核分枝杆菌肺病的流行病学特点及临床特征。方法 对本院收治的 41 例非结核分枝杆菌肺病的临床资料进行回顾分析。结果 治疗 6 月末，34 例患者临床症状缓解，21 例患者痰菌阴转。结论 扬州地区非结核分枝杆菌肺病多见于中老年及男性患者，农村居民多于城市居民，常合并有基础疾病，误诊率高，未见人传人现象。肺内病灶较广泛，多有空洞，常为薄壁空洞，耐药率高。经积极治疗后临床症状可缓解，肺内病灶可吸收好转，但痰菌阴转率低。

Objective To investigate the epidemiological characteristics and clinical features of non tuberculosis mycobacterium lung disease in Yangzhou. Methods The clinical data of 41 cases with non tuberculosis mycobacterium lung disease treated in our hospital were retrospectively analyzed. Results At the end of 6 months of treatment, 34 patients had the clinical symptoms relieved, and 21 patients had sputum negative conversion. Conclusion The non tuberculosis mycobacterium lung disease in Yangzhou is more common in the elderly and male patients. Rural residents are more susceptible than urban residents. The patients usually complicate underlying diseases and the misdiag- nosis rate is high and there is no human to human transmission phenomenon. Pulmonary lesions dis- tribute widely with cavities and thin-wall cavity, and it has high resistance rate in the patients. After the positive treatment, the clinical symptoms can be alleviated and pulmonary lesions can be partly absorbed, but the sputum negative conversion rate is low.