脂质蓄积指数与男性2型糖尿病患者非酒精性脂肪肝病的相关性研究

Correlation between lipid accumulation index and non-alcoholic fatty liver disease in male patients with type 2 diabetes mellitus

目的探讨脂质蓄积指数(LAP)与男性2型糖尿病(T2DM)患者合并非酒精性脂肪肝病(NAFLD)的相关性。方法随机选取128例男性T2DM患者,分为单纯T2DM组(A组)和T2DM合并NAFLD组(B组)。所有患者均测量腰围、血糖、甘油三酯等相关生化指标,计算LAP并做相关统计学分析。结果 B组的LAP显著高于A组(P<0.05),且LAP与Hb A1c、TG、SBP呈显著正相关(P<0.05)。应用LAP来预测男性T2DM患者NAFLD的受试者工作特征(ROC)曲线下面积是0.892,最佳切点是53.4。结论 LAP与男性2型糖尿病患者伴有非酒精性脂肪肝病密切相关。

Objective To investigate the correlation between lipid accumulation index （.LAP） and non-alcoholic fatty liver disease（NAELD） in male patients with type 2 diakrtes malitus（T2DM）. Methods A total of 128 male patients with T2DM were divided into simple T2DM group （group A） and T2DM with non-alcoholic fatty liver disease group （group B）. All patients measured waist circumference, blood glucose, triglyceride and biochemical indexes, and calculated LAP. Results LAP of group B was significantly higher than group A （ P 〈 0.05 ）, and LAP was positively correlated with HbA1c, TG and SBP （ P 〈 0.05 ）. The area under the receiver operating characteristic curve （ROC） of LAP in predicting male T2DM patients with non-alcoholic fatty liver disease was 0. 892. The optimal cut-off point was 53.4. Conclusion LAP is closely related with the non-alcoholic fatty liver disease in male patients with T2DM.